Bioelectronics: A Study in Cellular Regulations, Defense, by Albert Szent-Györgyi

By Albert Szent-Györgyi

Show description

Read or Download Bioelectronics: A Study in Cellular Regulations, Defense, and Cancer PDF

Similar engineering & transportation books

ACI 318-11: Building Code Requirements for Structural Concrete and Commentary (318-11)

The "Building Code necessities for Structural Concrete" ("Code") covers the fabrics, layout, and building of structural concrete utilized in constructions and the place acceptable in nonbuilding buildings. The Code additionally covers the power review of current concrete structures.

Among the topics coated are: agreement files; inspection; fabrics; longevity requisites; concrete caliber, blending, and putting; formwork; embedded pipes; development joints; reinforcement info; research and layout; energy and serviceability; flexural and axial rather a lot; shear and torsion; improvement and splices of reinforcement; slab platforms; partitions; footings; precast concrete; composite flexural individuals; prestressed concrete; shells and folded plate contributors; power overview of latest buildings; provisions for seismic layout; structural simple concrete; strut-and- tie modeling in Appendix A; substitute layout provisions in Appendix B; substitute load and energy aid components in Appendix C; and anchoring to concrete in Appendix D.

Extra info for Bioelectronics: A Study in Cellular Regulations, Defense, and Cancer

Example text

The two electrons, given off by the reductant in an oxi­ doreduction, can just as well be given off to a metallic electrode. Accordingly, most oxidoreductions lead to a welldefined redox potential. This is not the case in charge trans­ fer. Charge transfer is a very personal affair between an acceptor and donor which involves great intimacy, an orbital 31 II. ELECTRONIC MOBILITY overlap. Such orbital overlap is difficult to establish between the donor and a piece of metal. The lack of w^ell-defined redox potentials may also be one of the reasons w^hy the biological importance of charge transfer has not been fully recognized.

The conventional forces responsible for van der Waals attraction are attraction of charges or dipoles supported by the London dispersion forces. A force which has been overlooked till now is that of charge transfer. It will not pull particles together, but once they are brought together and orbital overlap has been established, it may help to hold the particles together 59 IV. PHYSIOLOGY AND PATHOLOGY and even bring them into positions in which the overlap is maximal (Mulliken). In a way, the "snaps" on ladies* dresses are analogous to charge transfer complexes: They have to be pushed together to hold.

What Fig. 28c suggests is that in a row of such charge transfer complexes (as may be the case in a membrane), the dipole developed in a charge transfer may promote the DA inter­ action with the next molecule, making charge transfer cooperative. The structures thus generated may be two- or three-dimensional. The surface of a protein molecule consists of the outer occupied orbitals, surrounded by the empty ones. So if two such molecules touch, their orbitals touch. Where energy relations are favorable, and an occupied orbital of high biopotential touches an empty orbital of equal or lower biopotential, charge transfer must take place.

Download PDF sample

Rated 4.37 of 5 – based on 46 votes